Cefepime Hydrochloride

Also known as: Maxipime, Cepimax, Feximac, Cefepim

CAS Number: 123171-59-5

4th generation cephalosporin — parenteral

Pharmacopeia Standards

USPEP

Mechanism of Action

Fourth-generation zwitterionic cephalosporin with enhanced outer membrane permeability in gram-negative bacteria. Binds PBP-1a, PBP-1b, PBP-2, PBP-3. Broad-spectrum coverage: gram-positive (MSSA, viridans streptococci, S. pneumoniae) and gram-negative (P. aeruginosa, Enterobacteriaceae including AmpC producers, H. influenzae). Stable against many plasmid-mediated and chromosomal beta-lactamases.

Technical Specifications

Generic / INN Name	Cefepime Hydrochloride
CAS Registry Number	123171-59-5
Molecular Formula	C19H25ClN6O5S2
Molecular Weight	532.96 g/mol
Typical Purity	97.0–103.0%
Storage Conditions	Store below 25°C; reconstituted solutions stable 24h at room temperature, 7 days refrigerated
Shelf Life	24 months from date of manufacture
Category	Cephalosporins

Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.

Typical Applications

Febrile neutropenia (empiric monotherapy), hospital-acquired and ventilator-associated pneumonia, complicated UTIs and pyelonephritis, complicated intra-abdominal infections (with metronidazole), nosocomial meningitis, Enterobacter/Pseudomonas infections, empiric therapy for serious healthcare-associated infections.