Ceftazidime Pentahydrate

Also known as: Fortaz, Tazicef, Kefadim, Ceptaz

CAS Number: 72558-82-8

3rd generation anti-pseudomonal cephalosporin — parenteral

Pharmacopeia Standards

USPEPBP

Mechanism of Action

Third-generation cephalosporin with unique pyridinium substituent that confers exceptional anti-pseudomonal activity, including against strains resistant to other beta-lactams. Binds PBP-3 (primary). Stable to most plasmid-mediated beta-lactamases but susceptible to ESBLs. Bactericidal.

Technical Specifications

Generic / INN Name	Ceftazidime Pentahydrate
CAS Registry Number	72558-82-8
Molecular Formula	C22H22N6O7S2·5H2O
Molecular Weight	636.65 g/mol
Typical Purity	97.0–102.0% (anhydrous basis)
Storage Conditions	Store below 25°C, protected from light
Shelf Life	24 months from date of manufacture
Category	Cephalosporins

Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.

Typical Applications

Pseudomonas aeruginosa infections (respiratory, urinary, wound), febrile neutropenia (often with aminoglycoside or vancomycin), bacterial meningitis (P. aeruginosa), cystic fibrosis pulmonary exacerbations, nosocomial pneumonia, complicated UTIs with Pseudomonas risk.