Ciclopirox Olamine
Also known as: Loprox, Batrafen, Penlac, Stieprox, Ciclopirox Shampoo, Dandrazol CP
CAS Number: 41621-49-2
Hydroxypyridone antifungal — topical, broad spectrum
Pharmacopeia Standards
Mechanism of Action
Ciclopirox is not a sterol-pathway inhibitor; it chelates polyvalent cations, particularly Fe3+ and Al3+, and thereby inactivates metal-dependent fungal enzymes including cytochromes and catalase. Loss of these enzymes disrupts mitochondrial electron transport, membrane transport and peroxide degradation, killing the organism. Because the mechanism is distinct from the azoles and allylamines, there is no cross-resistance, and it retains activity against bacteria and Malassezia as well as dermatophytes.
Technical Specifications
| Generic / INN Name | Ciclopirox Olamine |
| CAS Registry Number | 41621-49-2 |
| Molecular Formula | C12H17NO2·C2H7NO |
| Molecular Weight | 268.35 g/mol |
| Typical Purity | 98.5–101.0% (on anhydrous basis) |
| Storage Conditions | Store below 25°C in tightly closed, light-resistant containers in a dry place; protect from light and moisture |
| Shelf Life | 48 months from date of manufacture |
| Category | Antifungals |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
Seborrhoeic dermatitis and dandruff, tinea pedis, cruris and corporis, cutaneous candidiasis, pityriasis versicolor, onychomycosis as medicated nail lacquer, vulvovaginal candidiasis
Manufacturers (0+)
View all →Do you manufacture Ciclopirox Olamine? Add your free listing and reach global buyers.
Add listing — FreeCan you supply Ciclopirox Olamine? List as an authorised distributor or export house.
Register as traderEarn commission by connecting buyers with verified API suppliers. Free to join.
Become an agent