Dicloxacillin Sodium
Also known as: Dynapen, Diclocil, Pathocil, Dicloxin
CAS Number: 343-55-5
Penicillinase-Resistant Isoxazolyl Penicillin (Beta-Lactam)
Pharmacopeia Standards
Mechanism of Action
Dicloxacillin carries a dichlorophenyl isoxazolyl side chain that provides even greater steric protection against staphylococcal beta-lactamase than cloxacillin. The protected beta-lactam ring acylates penicillin-binding proteins and prevents the transpeptidation step of peptidoglycan assembly. High plasma protein binding and superior oral bioavailability relative to cloxacillin make it the preferred oral agent in this subclass.
Technical Specifications
| Generic / INN Name | Dicloxacillin Sodium |
| CAS Registry Number | 343-55-5 |
| Molecular Formula | C19H16Cl2N3NaO5S |
| Molecular Weight | 492.31 g/mol (anhydrous); 510.32 g/mol (monohydrate) g/mol |
| Typical Purity | NLT 90.0% dicloxacillin sodium on the anhydrous basis; individual impurity NMT 1.0% |
| Storage Conditions | Store in tight containers below 25 C, protected from light and moisture. |
| Shelf Life | 36 months in original sealed packaging |
| Category | Penicillins |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
Oral capsules and dry powder for suspension; fixed-dose oral combinations in emerging markets; skin and soft-tissue infection product lines.
Manufacturers (0+)
View all →Do you manufacture Dicloxacillin Sodium? Add your free listing and reach global buyers.
Add listing — FreeCan you supply Dicloxacillin Sodium? List as an authorised distributor or export house.
Register as traderEarn commission by connecting buyers with verified API suppliers. Free to join.
Become an agent