Enrofloxacin
Also known as: Baytril, Enroxil, Enrotril, Floxidin, Enrocin
CAS Number: 93106-60-6
Veterinary fluoroquinolone antibacterial
Pharmacopeia Standards
Mechanism of Action
Enrofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, trapping the enzyme-DNA cleavage complex and preventing supercoiling and strand religation, which is rapidly bactericidal and concentration-dependent. Its spectrum spans Gram-negative pathogens, many Gram-positive organisms and Mycoplasma, with excellent tissue and intracellular penetration. In the target animal it is partly de-ethylated to ciprofloxacin, which contributes to the overall antibacterial effect.
Technical Specifications
| Generic / INN Name | Enrofloxacin |
| CAS Registry Number | 93106-60-6 |
| Molecular Formula | C19H22FN3O3 |
| Molecular Weight | 359.40 g/mol g/mol |
| Typical Purity | 98.0-102.0% on anhydrous basis (USP/EP); ciprofloxacin content within monograph limit |
| Storage Conditions | Store in tight, light-resistant containers below 30 C in a dry place, protect from light |
| Shelf Life | 48 months from date of manufacture |
| Category | Veterinary Antibiotics |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
Injectable solutions, oral tablets, oral solutions and water-soluble powders for cattle, swine, poultry, dogs and cats; otic preparations for canine otitis; and treatment of colibacillosis, respiratory disease and soft tissue infection.
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