Ivermectin
Also known as: Mectizan, Stromectol, Ivermol, Ivecop, Soolantra, Scabiover
CAS Number: 70288-86-7
Antiparasitic / Anthelmintic (Macrocyclic Lactone, Avermectin)
Pharmacopeia Standards
Mechanism of Action
Ivermectin binds with high affinity to glutamate-gated chloride channels found in invertebrate nerve and muscle cells, driving a sustained chloride influx that hyperpolarises the membrane. The parasite is paralysed and dies, while mammals are largely spared because these channels are absent and the blood-brain barrier restricts CNS penetration. It also potentiates GABA-gated chloride transmission in susceptible invertebrates.
Technical Specifications
| Generic / INN Name | Ivermectin |
| CAS Registry Number | 70288-86-7 |
| Molecular Formula | C48H74O14 (H2B1a, ≥90%) and C47H72O14 (H2B1b, ≤10%) |
| Molecular Weight | 875.10 g/mol (H2B1a component) g/mol |
| Typical Purity | Not less than 95.0% total avermectins with not less than 90.0% H2B1a component (HPLC) |
| Storage Conditions | Store in tight, light-resistant containers at 2–8°C or below 25°C as qualified; protect from light and oxygen |
| Shelf Life | 36 months in original sealed packaging under recommended conditions |
| Category | Anthelmintics |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
Tablets for onchocerciasis, lymphatic filariasis, strongyloidiasis and scabies; topical creams and lotions for rosacea and head lice; very large veterinary injectable, pour-on and oral segments.
Manufacturers (0+)
View all →Do you manufacture Ivermectin? Add your free listing and reach global buyers.
Add listing — FreeCan you supply Ivermectin? List as an authorised distributor or export house.
Register as traderEarn commission by connecting buyers with verified API suppliers. Free to join.
Become an agent