Levamisole Hydrochloride
Also known as: Ergamisol, Decaris, Ketrax, Vermisol, Levasole, Nilverm
CAS Number: 16595-80-5
Anthelmintic / Immunomodulator (Imidazothiazole)
Pharmacopeia Standards
Mechanism of Action
Levamisole is a selective agonist at nicotinic acetylcholine receptors on nematode muscle, producing sustained depolarisation, spastic paralysis and expulsion of the worm by peristalsis. It is the levo-isomer of tetramisole and carries essentially all of the racemate’s anthelmintic activity. Separately, it stimulates T-cell and macrophage function, which underpins its historical use as an adjuvant immunomodulator.
Technical Specifications
| Generic / INN Name | Levamisole Hydrochloride |
| CAS Registry Number | 16595-80-5 |
| Molecular Formula | C11H12N2S · HCl |
| Molecular Weight | 240.75 g/mol g/mol |
| Typical Purity | Not less than 99.0% (assay), on the dried basis |
| Storage Conditions | Store in tight, light-resistant containers below 30°C; protect from light and moisture |
| Shelf Life | 60 months in original sealed packaging |
| Category | Anthelmintics |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
Tablets and oral solutions for ascariasis and hookworm; immunomodulatory adjunct in nephrotic syndrome regimens; very large veterinary anthelmintic and immunostimulant market in cattle, sheep, pigs and poultry.
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