Meropenem Trihydrate
Also known as: Merrem, Meronem, Meropenem Fresenius, Merowin
CAS Number: 119478-56-7
Carbapenem — broad-spectrum parenteral beta-lactam
Pharmacopeia Standards
Mechanism of Action
Carbapenem beta-lactam with the broadest antibacterial spectrum among available antibiotics. Inhibits cell wall synthesis by binding PBP-2 (primary in gram-negatives) and PBP-3 (gram-positives). Stable to nearly all chromosomal and plasmid-mediated beta-lactamases including ESBLs; susceptible only to carbapenemases (KPC, NDM, OXA-48). Penetrates gram-negative outer membrane via OmpF/OmpC porins.
Technical Specifications
| Generic / INN Name | Meropenem Trihydrate |
| CAS Registry Number | 119478-56-7 |
| Molecular Formula | C17H25N3O5S·3H2O |
| Molecular Weight | 437.51 g/mol |
| Typical Purity | 98.0–102.0% (anhydrous basis) |
| Storage Conditions | Store below 25°C, protected from moisture |
| Shelf Life | 24 months from date of manufacture |
| Category | Carbapenems |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
Hospital-acquired and ventilator-associated pneumonia, complicated intra-abdominal infections (gold standard), febrile neutropenia (monotherapy), bacterial meningitis (resistant gram-negatives), complicated UTIs, septicemia, skin/soft tissue infections, empiric therapy for MDR gram-negative infections including ESBL-producers.
Manufacturers (2+)
View all →India
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