Teicoplanin
Also known as: Targocid, Teicolin
CAS Number: 61036-62-2
Glycopeptide antibiotic — gram-positive infections including MRSA
Pharmacopeia Standards
Mechanism of Action
Glycopeptide with same D-Ala-D-Ala binding mechanism as vancomycin. Complex mixture of 6 components (TA2-1, TA2-2, TA2-3, TA2-4, TA2-5, TA3-1). Lipophilic fatty acid chains enable self-association and membrane anchoring, explaining its long half-life (~100h) and once-daily dosing. Less nephrotoxic than vancomycin; does not require TDM in standard dosing.
Technical Specifications
| Generic / INN Name | Teicoplanin |
| CAS Registry Number | 61036-62-2 |
| Molecular Formula | Complex glycopeptide mixture (TA2-1 to TA3-1 components) |
| Molecular Weight | ~1879 g/mol |
| Typical Purity | Sum of 5 principal components NLT 80% (BP/EP component ratio specification) |
| Storage Conditions | Store below 25°C, protect from light |
| Shelf Life | 24 months from date of manufacture |
| Category | Glycopeptides |
Specifications are indicative and intended for sourcing reference only. Always confirm against the supplier's Certificate of Analysis and the applicable pharmacopeial monograph before issuing a purchase specification.
Typical Applications
MRSA infections (Europe/Asia first-line alternative to vancomycin), gram-positive endocarditis, osteomyelitis, bacteremia, diabetic foot infections, surgical prophylaxis (joint replacement, cardiac), C. difficile colitis (oral — not absorbed systemically).
Manufacturers (0+)
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